The numbering reflects the level of the signal you are putting into it. As Kubi said, a lower input level requires more amplification.
Note that this only really makes sense with a pre that also has an output level pot or attenuator. The ideal gain staging from a noise performance perspective (sweeping generalization) is to always set the amplification to the most possible before clipping occurs, then attenuate the signal to the desired level for the next stage, a compressor, recorder, a/d converter, etc. If you notice many old pres, altec/rca/langevin/telefunken, were fixed gain and the lineamps meant to follow them always had a volume pot on the input. You can start to visualize how that gain staging worked. See some posts from NYDave and PRR about how it was done in the good ol' days.
Sorry for the long post, but I have only begun to understand how this stuff has evolved and where the confusion arises since I started reading all these wonderful posts from the knowledgeable folks around here.