The pictures are a little big to be able to view them as a whole on my device but...
A few things that jump out:
To keep hum down you'll need to ground the centre-tap of your heater winding rather than let it just float. Elevating an AC heater supply by about 25 volts with respect to cathode can help further if needed. Do that with a divider from the clean H.T. and the cap bypassed 25V injected at the 6V3 AC C.T.
Looking at the specs of your specified Hammond power transformer (269BX), the HV winding isn't 117VAC but 300C C.T., so copying the original Altec voltage doubler will be a no-no.
If you already have that transformer then use a full wave bridge across the whole winding and plan on losing over 150V DC in wasted heat with larger series resistors in the filter banks.
However, if you can, buy the Hammond 269
AX instead with 250V AC C.T. and you won't need to lose so much DC voltage.
The dual pot at the input is supposed to be sized to appropriately terminate the input transformer so I wouldn't assume a dual 50K is correct for all input types.
On a particular transformer I used, a dual 25K was more appropriate. Just giving a heads up here, not pointing out an error.
However, a dual 50K is WAY too high a value for the output - in terms of load on the output transformer, but more importantly in terms of presenting a high source impedance to the outside world at most settings.
The simplest output level control would be a single 1K log and would be a decent all round load for the output transformer and be a low source impedance (approx 250r at worst case) to send down the cable.
I don't know what the ratio is of the Sowter output transformer but, last I looked, the ratio they were specifying for an Altec was higher than original.
You're ideally looking for about a 7:1 turns/voltage ratio. So a 30K:600. Others have used slightly lower ratios so there is a little leeway. But 7:1 was what worked for me.
The meter wouldn't generally be your lower specified 1mA, never mind a 100mA.
Just use a decent VU meter with the internal diode rectifier removed.
When laying out your actual PCB, use the same good practices you would if it were a point-to-point layout. This has been posted before, but Merlin's page here:
http://www.valvewizard.co.uk/Grounding.htmlis a good guide to follow. Not only in terms of grounding, but with respect to keeping the current of each stage tightly contained within its own small loop. Doesn't matter if it's point-to-point or a pcb, the same rules apply.