I use Bourns 3266 series sealed multi-turn trimmers, although i believe I've also used some TT electronics ones in prototypes.
We leave them in rather than using a fixed resistor on the products we use them in (V14, V24, and V1).
In order to make sure they don't move once we bias, we'll do a dab of 1401 adhesive (we use the red "C" but there's also blue "B" and clear "A) against the side of the thread which helps lock it in place.
For the V14/V24 it tunes the capsule polarization voltage, and for V1 it gets the JFET biased properly.
I guess if there's no filtering in place it could cause more noise than a high-grade metal film resistor, but good filtering ought to be in place for those types of spots anyways.